As soon as you complete Konley's first quest, Last of the Crystal Mystics, he gives you this quest. Note that if you can time it such that you're working on Part 2 of this quest at the same time as Part 2 of the Making Light quest, your Prismatic Lily will count towards both.
Additionally, if you can afford the inventory space to hold on to them that long, the Foxfire Potions you make for Part 1 of the Making Light quest will come in handy when you reach Part 3 of this quest.
As soon as you complete this quest, Konley will give you his In Search of Sapphire quest.
Part 1 of 3
Obtain 1 pile of Crystal Sand
Make 1 Crystal Ball
Make 1 pair of Rose-tinted Goggles
Part 2 of 3
Claim the land of the Crystal Henge
Send Konley to the Crystal Henge
Find 1 Prismatic Lily
Part 3 of 3
Have 1 plot of Mystic Mushrooms
Make 4 Foxfire Potions
Make 1 Frozen Crystal Ball